Now on Brain-CODE: New EpLink multi-modal dataset on temporal lobe epilepsy and surgical outcomes
January 7, 2026
The Ontario Brain Institute has released a comprehensive dataset from the Epilepsy Research Program (EpLink), a former OBI Integrated Discovery Program, offering insights into temporal lobe epilepsy and surgical outcomes. Available now on Brain-CODE, OBI's neuroinformatics platform, this deeply phenotyped multi-modal resource features 118 patients, including 72 with surgical outcomes, from two Ontario epilepsy surgical centers.
Epilepsy is one of the most common neurological conditions, affecting people of all ages across Ontario. For many with temporal lobe epilepsy — the most common form of epilepsy in adults — surgery can offer life-changing relief from seizures. However, predicting which patients will benefit most from surgery and how to minimize cognitive side effects like memory loss has remained challenging.
What's included:
- Structural MRI – Detailed anatomical brain imaging
- Diffusion Imaging – Mapping of neural pathways and connectivity
- Resting State fMRI – Brain network activity patterns
- EEG Data – Electrical brain activity recordings
- Clinical Information – Seizure information, treatments, and cognitive assessments
- Surgical Outcomes – Long-term results including seizure control and memory function
- Patient Demographics – Background and medical history
Led by Dr. Mary Pat McAndrews (UHN), Dr. Ali R. Khan, Dr. Terry M. Peters, and Dr. Ingrid Johnsrude (Western University), the research team's goal was to help patients and families understand not only whether surgery will stop seizures, but also how it might affect memory and thinking. This comprehensive collection connects specific brain features with both clinical symptoms and treatment results. By examining structure, connectivity, and function together, the dataset enables researchers to understand why some patients respond better to surgery than others.
As part of OBI's commitment to open science, these data are now available on Brain-CODE. By providing the global research community with access to standardized, high-quality clinical and imaging data, OBI is enabling scientists to collaborate across institutions and borders. This collaborative approach is essential for developing better predictive tools, refining treatment approaches, and working toward personalized care for people with temporal lobe epilepsy.
> EXPLORE THESE DATA ON BRAIN-CODE